12th Annual DeGregorio Family Foundation Grant Award for Cancers of the Esophagus and Stomach
The DeGregorio Family Foundation for Gastric and Esophageal Cancer is pleased to announce our 12th annual funding opportunity for gastroesophageal malignancies. The Foundation seeks to promote and facilitate collaborative research on the pathogenesis, early diagnosis, and treatment of upper gastrointestinal malignancies. We support high quality, innovative, and transformative translational and bench research to improve the understanding of the biology of these diseases, identification of potential novel therapeutic targets, or in the development and evaluation of novel biomarkers for early diagnosis and treatment. Pre-clinical research, basic mechanistic studies, genomic/epigenomic studies, as well as epidemiologic studies may also be supported
Applications currently under review
Thanks to a generous anonymous donor, this year we are able to support up to two additional grants for gastroesophageal malignancies with the same guidelines as above and the same protocol. These Special Grant Awards have an earlier deadline of July 15, 2021.
Application Timeline and Grant Details - Applications Currently Under Review
Deadline: November 2, 2021. Up to $250,000 over two years will be awarded.
Funding Period: January 15, 2022 – January 14, 2024
Amount: $250,000 for entire grant period. (Indirect costs cannot exceed 10%, and the entire grant cannot exceed $250,000.)
Deadline for applications: Tuesday, Nov. 2, 2021
Eligibility: The Foundation must be associated with an academic or medical institution possessing a tax-exempt status under section 501(c)(3) of the IRS code.
We are not accepting applications from postdocs. Research projects must not be funded currently under a separate mechanism.
Research projects are selected through a rigorous review process, and project goals must align with the DeGregorio Family Foundation’s mission. The Foundation’s application review process is guided by its Scientific Advisory Board. Criteria for successful grants are impact, the likelihood of completion, and making a significant contribution to understanding, diagnosing. or treating gastric or esophageal malignancies. The intention of this award is to provide seed funding for research in upper GI malignancies. Funded applicants are expected to apply for subsequent peer-reviewed support (i.e. NIH or similar agency).
We wish all the applicants luck and we hope to announce winners by mid-January.
Accountability:
Funding will be divided into three installments. The first installment will be provided when appropriate institutional approvals are submitted and the study is underway. The 2nd installment is contingent upon submission and review of an interim report at 1 year, and the final installment will be contingent upon receipt of a final study report.
Any publications or presentations resulting from this research must be acknowledged.
Applications Timeline and Further Details
We owe him a debt of gratitude for our ongoing success.” Lynn DeGregorio, President Founder
The DeGregorio Family for Gastric and Esophageal Cancer (Gastroesophageal Cancer) is pleased to announce its 13th annual funding opportunity for gastroesophageal malignancies in honor of Michael F. Price. The Foundation seeks to promote and facilitate collaborative research on the pathogenesis, early diagnosis and treatment of upper gastrointestinal malignancies. We support high quality, innovative and transformative translational and bench research to improve the understanding of the biology of these diseases, identification of potential novel therapeutic targets, or in the development and evaluation of novel biomarkers for early diagnosis and treatment. Pre-clinical research, basic mechanistic studies, genomic/epigenomic studies as well as epidemiologic studies may also be supported.
Funding: $250,000 over 2 years.
Indirect costs: 10%,
The deadline for applications is November 1, 2022. Funding period: January 15, 2023 – January 14, 2025. Winners announced: mid-January 2023.
(in lieu of our November grants)
The DeGregorio Family Foundation (DFF) is issuing an RFA for up to $500,000 for a grant proposing novel technology or new approaches for target discovery or treatment in gastroesophageal cancer.
Investigators new to the field and not currently funded for gastroesophageal cancer research are encouraged to apply. The timeline for the submission process is provided below. One to three grants will be awarded with completion dates spanning two to three years. Grants may be supported in full or partially based on the aims of the project, novelty and feasibility.
Request For Applications
Despite the recent drug approvals for the treatment of gastric and esophageal cancers, these diseases continue to have high morbidity and mortality. The DeGregorio Foundation is focused on supporting research that has the potential to greatly impact patient care and significantly advance the management of patients with gastric or esophageal carcinoma. We encourage novel concepts and new technology, with a goal to bring these advances to patients with gastroesophageal cancer. We would like to promote team science and inclusion of individuals who are new to gastroesophageal cancer research.
The Torrey Coast Foundation will match funds from the DeGregorio Family Foundation to support the grant and the awarded party(ies) will collaborate with the Torrey Coast Foundation GEMINI group www.teamgemini.org.
Grantees will have access to a supply of gastroesophageal cell lines, patient-derived organoids and mouse models to help facilitate research projects. A good idea shall not die because of a lack of resources.
Funding – Up to $500,000 over 2 to 3 years. Indirect costs – 15%
Instructions: All applicants are required to submit a letter of intent (no more than 2 pages, 11 size font, 0.75 in margins) indicating the title, background, aims, and abbreviated research plan, and institution(s) involved. On a separate page, include high-level budget divided by aims.
Applicants invited to submit full Proposals notified: Wednesday, August 30, 2023
Zoom call for finalists: Friday, September 8, 2023, 9:00 to 11:30 a.m. ET
Proposal deadline for finalists: Tuesday, October 10, 2023
Grant(s) Awarded: Mid-December 2023
Funding Period: December 15, 2023 – December 15, 2026
Eligibility: The Foundation must be associated with an academic or medical institution possessing a tax-exempt status under section 501(c)(3) of the IRS code.
We are not accepting applications from postdocs.
Research projects must not be funded currently under a separate mechanism. Research projects are selected through a rigorous review process. The Foundation’s application review process is guided by its Scientific Advisory Board headed by Dr. Manish A. Shah.
Any publications or presentations resulting from this research must be acknowledged.
Any questions should be sent in writing to sarah@degregorio.org and will be answered in an expeditious manner.