2026 Information coming soon.
The DeGregorio Family Foundation in partnership with the Torrey Coast Foundation is pleased to announce an RFA for up to $2 million regarding gastroesophageal cancer malignancies.
Request for Applications
The RFA is for existing or new drug development for an early phase clinical trial or for a late-stage research project ready for IND-enabling studies that may advance our understanding of gastroesophageal cancer and lead us to impacting patient care. Completion date should be between 1 to 3 years. Grants may be supported in full or partially based on the aims of the project, novelty and feasibility.
Funding – Up to $2 million over 1 to 3 years, including indirect costs – 15%.
Eligibility:
Applicants must be employed by a non-profit academic institution. Applications will be accepted from both U.S. and non-U.S. entities.No applications will be accepted from post-docs, or individuals without a faculty appointment.We encourage interdisciplinary collaborations and welcome proposals from independent investigators at all career stages, especially those new to the field of upper GI cancers.Proposals that include a clinical trial will require a clinical trial budget, and commitment for the study drug.
Other caveats:
Please do not submit the same grant application to the DeGregorio Family Foundation as from a previous grant cycle unless the Foundation has specifically requested that you do so.Research projects must not be funded currently under a separate mechanism. Research projects are selected through a rigorous review process. The Foundation’s application review process is guided by its Scientific Advisory Board headed by Dr. Manish A. Shah.
Instructions:
All applicants are required to submit a letter of intent (no more than 2 pages, 11 size font, 0.75 margins) indicating the title, background, aims and abbreviated plan, and institution(s) and key investigators involved. Please include high-level budget and deliverables for each aim in the 2 pages.
The LOI and budget are due Monday, June 16, 2025.Applicants selected for a full proposal will be advised by Monday, July 21, 2025. Final applications due Friday, September 5, 2025
Deadlines:
June 16, 2025, 11:59 p.m. EDT – Letters of intent due.
July 21, 2025 – Applicants selected for full proposal notified.
September 5, 2025, 11:59 p.m. EDT – Applications due.
November 2025 – Winner(s) announced.
Any publications or presentations resulting from this research must be acknowledged.
Any questions should be sent in writing to sarah@degregorio.org and will be answered in an expeditious manner.